Scientists will be able to use this solution to better analyze how metabolite levels are related to metabolic fluxes and protein levels within complex systems. This technique will be made available for use by researchers around the world for their own evaluation in metabolomics research. An interview with Professor Lesley JonesNew research from TSRI and Salk points to reason behind debilitating nerve diseaseThe QTRAP 5500 System is certainly a mass spectrometry system that integrates triple quadrupole and linear accelerator trap technology onto an individual platform for quicker and more accurate analysis of complex samples, making this operational system ideal for metabolomics, in addition to the areas of systems biology including lipidomics and proteomics.All were of normal weight, but about half carried a mutation that place them at risk for obesity. The researchers found that the pro-obesity mutation activated two additional genes called IRX3 and IRX5, which are inside cells that produce fat tissue. Most people think of weight control in terms of exercise versus food, Kellis said. If you burn more calories than you take in, you can expect to lose weight then. However the body can burn off fat as heat also, an activity called thermogenesis. This process kicks in when you are out into the frosty, for example, losing fat to keep you warm and working, Kellis said. IRX3 and IRX5 become get better at controllers of the thermogenesis procedure, ordering your body to store excessive energy in body fat cells than burning up it off rather, the researchers found.